The cees dekker Diaries
The cees dekker Diaries
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Rotary movement of DNA rotors on nanopores. Best row: Uncooked movie in the Cy5 channel of each and every rotor. Middle row: corresponding one-particle localization benefits of both finishes from the DNA rotors. The situation of the current body is marked as orange and blue dots, and also the trajectory of The ten frames just before The existing frame is demonstrated as strong strains.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I
Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Microbiology has only existed for your century, considering the fact that we began to study micro-organisms much more critically. I believed nanobiology was an proper phrase, due to the fact all molecular Organic appropriate interactions happen for the nanoscale: a protein is some nanometres in dimensions, DNA is two nm thick.’
All parameters had been precisely the same for every panel During this video, except for the initial placement in the 6hb rod (proven in blue) about the nanopore. Simulations that terminated early as a consequence of translocation of the rod with the pore are marked by a grey track record.
2011, first in vitro measurements of transportation throughout one biomimetic nuclear pore intricate; growth of multiplexed magnetic tweezers for kilo-molecule experiments; and cees dekker solved the mechanism of homology recognition in DNA homologous recombination
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one). The present–voltage curves confirmed considerable modulations with gate voltage, even at home temperature, which was in step with band bending inside of a ~0.6 eV bandgap semiconducting nanotube. These details also showed which the conductance could possibly be modulated by 6 orders of magnitude by altering the gate voltage. The final results of this operate — a room-temperature transistor made out of only one carbon nanotube molecule — had been released in Nature in May possibly 1998.
Screening pseudotopological and nontopological styles for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments
Quite a few new phenomena ended up learned, and he and his investigation team established a number one placement During this industry of research. Dekker and his exploration group found out new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the 1st to construct a transistor dependant on just one nanotube molecule.
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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in red, plus a 3D rendering of the movement of the DNA rod is shown.